This is how long it takes for Accutane to start working

The NHS warns that the dosage of Accutane is different in everyone depending on body weight, so it is important to speak to your doctor before taking it. The source adds that people taking Accutane can expect the therapy to last around 16 to 24 weeks, with significant improvements in the surface of the skin for eight weeks after stopping treatment. Most people have clearer skin at this stage, but others may need a second round of treatment.

Much of the effectiveness of isotretinoin treatment will be determined by whether you take the correct dosage and adhere to some of the best practices related to the drug. Some of these best practices include swallowing the capsule with about eight ounces of water and making sure you don’t take the medication on an empty stomach (via Mayo Clinic). The source also advises against breaking, crushing, or sucking on the capsules.

As for the average dose, it may vary depending on your health condition, so it is best to stick to your doctor’s prescription. As a guide, Drugs.com notes that adults can take 0.25 to 2 mg/kg isotretinoin by mouth 2 times a day for up to 20 weeks. The same goes for kids 12 or older who struggle with acne.