Diabetes may increase long-term COVID risk
Diabetes may increase the risk of long COVID, new analyzes from seven previous studies suggest.
The researchers looked at studies that followed people for at least four weeks after recovering from COVID-19 to see which people developed persistent symptoms associated with long COVID, such as brain fog, skin conditions, depression and shortness of breath. In three of the studies, people with diabetes were up to four times more likely to develop long COVID than people without diabetes, according to a presentation Sunday at the American Diabetes Association’s annual scientific sessions. The researchers said diabetes appears to be “a potent risk factor” for long COVID, but their results are preliminary because studies used different methods, definitions of long COVID and lengths of follow-up, and some looked at hospitalized patients. while others have focused on people with milder cases of COVID-19.
“More high-quality studies across multiple populations and settings are needed to determine whether diabetes is indeed a risk factor” for long COVID, the researchers said. “In the meantime, careful monitoring of people with diabetes…may be advised” post-COVID-19.
COVID-19 in pregnancy linked to babies’ learning abilities
Babies born to mothers who had COVID-19 during pregnancy may be at higher than average risk of brain development problems involved in learning, concentration, memory and social skill development, researchers have found. researchers.
They studied 7,772 infants born in Massachusetts between March and September 2020, following the babies up to 12 months of age. During this period, 14.4% of babies born to the 222 women with a positive coronavirus test during pregnancy were diagnosed with a neurodevelopmental disorder, compared to 8.7% of babies whose mothers avoided the virus during pregnancy. After controlling for other neurodevelopmental risk factors, including preterm delivery, SARS-CoV-2 infection during pregnancy was linked to an 86% higher risk of neurodevelopmental disorder diagnosis in offspring. , the researchers reported Thursday in JAMA Network Open. The risk was more than doubled when the infection occurred during the third trimester.
The researchers emphasize that their study was brief and cannot rule out the possibility that additional neurodevelopmental effects become apparent as children grow older. On the other hand, they note, larger and more rigorous studies are needed to rule out other potential causes and prove that the coronavirus is to blame.
Rare post-COVID-19 syndrome in children is less common now
The rare but life-threatening inflammatory syndrome seen in some children after coronavirus infection has become even rarer, with the Omicron variant causing most infections and more vaccinated children, according to a new study.
The researchers looked at data from Denmark on more than half a million children and adolescents infected after Omicron became dominant, about half of whom experienced breakthrough infections after vaccination. Overall, only one vaccinated child and 11 unvaccinated children developed multisystem inflammatory syndrome in children (MIS-C), which causes inflammation of the heart, lungs, kidneys and brain after mild or asymptomatic infection. by SARS-CoV-2. This translates to rates of 34.9 cases of MIS-C per million unvaccinated children with COVID-19 and 3.7 cases per million young patients vaccinated with COVID-19, the researchers said on Wednesday in JAMA Pediatrics. By comparison, the rates of MIS-C cases when Delta was predominant were 290.7 per million unvaccinated infected children and 101.5 per million among those vaccinated who had COVID, they said.
The fact that the risk of MIS-C was significantly lower in vaccinated children suggests that the vaccine helps prevent the immune system from causing the deadly inflammatory reaction that is a hallmark of MIS-C, the researchers said.